Summaries by Inventor Murphy, Theresa
Murphy, Kenneth ; Murphy, Theresa ; Watanabe, Norihiko ; Yang, Jianfei
T-004061
— Background: B and T lymphocyte attenuator (BTLA or CD272) is an inhibitory receptor expressed on T and B cells, dendritic cells and select myeloid cells. BTLA interacts with costimulatory molecule herpesvirus entry mediator (HVEM, Tnfrsf14, ATAR, HVEA, LIGHTR, or TR2). When bound to BTLA, HVEM atten…
B6.129.Btla tm1kmm/J MouseMurphy, Kenneth ; Murphy, Theresa
T-014100
— Notes: Btla-/- knockout mouse with a 129S/SvEv background. B6.129.Btla tm1kmm/J Mouse.
Modulation of Lymphocyte ActivityMurphy, Kenneth ; Murphy, Theresa ; Watanabe, Norihiko ; Yang, Jianfei
T-004061
— Background: B and T lymphocyte attenuator (BTLA or CD272) is an inhibitory receptor expressed on T and B cells, dendritic cells and select myeloid cells. BTLA interacts with costimulatory molecule herpesvirus entry mediator (HVEM, Tnfrsf14, ATAR, HVEA, LIGHTR, or TR2). When bound to BTLA, HVEM atten…
Hamster Hybridoma producing Monoclonal Antibody against Murine CD272 (BTLA)Hurchla, Michelle ; Murphy, Kenneth ; Murphy, Theresa ; Sedy, John
T-004458
— Target: B and T lymphocyte attenuator (BTLA). BTLA is expressed on peripheral lymphocytes, splenic macrophages and select developing B and T cells.Inventors created the monoclonal antibodies by immunizing Armenian hamster or BALB/c background BTLA -/- mice. Hamster monoclonal 6A6 is of the IgG isotype, whereas all murine Abs are IgG1κ. Some of the antibodies recognize the mouse BTLA C57/BL6 allele (6A6, 3F9.C6) and some are panspecific (…
Xcr1 IRES mCherry-hCre Mouse StrainDurai, Vivek ; Murphy, Kenneth ; Murphy, Theresa
T-019142
— Xcr1 IRES mCherry-hCre Mouse Strain This genetically modified mouse strain expresses the fluorescent marker mCherry and a human codon optimzed Cre in the same transcript as the chemokine receptor XCR1. XCR1 is specifically expressed in cDC1s, allowing specific deletion of genes in and the fluoresce…
Knockout Mouse lacking Expression of the Batf3 GeneDiamond, Michael ; Murphy, Kenneth ; Murphy, Theresa ; Schreiber, Robert ; Unanue, Emil
T-009136
— Notes: Batf3-/- knockout mouse with a 129SvEv background.
